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Synthetic glue Glubran 2

Synthetic glue Glubran 2, GEM Italy
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Manufacturer: GEM Italy
Viareggio , Italy

The synthetic glue is based on N-butyl cyanoacrylate, modified by adding a monomer developed by the manufacturer. It represents a pale-yellow transparent ready for use liquid.







Синтетический клей на основе N-бутилцианоакрилата, модифицирован добавлением разработанного производителем мономера. Представляет собой бледно-жёлтую прозрачную жидкость, готовую к использованию.
Code number Name Volume Quantity (pieces / box)
G-NB2-100 Surgical glue Glubran2 1 ml 10
G-NB2-50 Surgical glue Glubran2 0,5 ml 10
G-NB2-25 Surgical glue Glubran2 0,25 ml 10
G-NBOC2 Two-component skin glue Glubran2 0,5 ml 10
G-NBOC2-35 Two-component skin glue Glubran2 0,35 ml 10
G-NBOC2-25 Two-component skin glue Glubran2 0,25 ml 10

Properties

Adhesive
High tensile strength. The minimum allowable loading is 18 kg/cm2, which significantly exceeds both physiological and pathological abdominal pressure rates.

Sealant
Due to its synthetic nature and high strength adhesive composition, Glubran 2 forms a thin elastic film having a gas and structural composition and does not change when interacting with blood or other body fluids.

Hemostatic
Hemostasis is achieved as a result of mechanical action; blood clots are formed during a chemical reaction. It is an excellent remedy for stopping oozing and capillary bleeding.

Bacteriostat
During polymerization, the glue forms an effective antiseptic barrier against pathogens of the most common infections found for up to 7 days in the surgical environments.

Sclerosant
Under intravascular administration "Glubran 2" leads to the vessel occlusion with the local thrombosis formation and fibrosis and sclerosis as a result.

Liquid embolizer
Under intravascular administration, Glubran 2 polymerizes with a clot formation that due to its high adhesion force adheres tightly to the vessel wall causing embolization.

Description
  • Can be kept at the room temperature (22.5 +/- 2.5°C) for 48 hours
  • Ready to use
  • Does not polymerize in the air
  • Effective in a wet environment
  • Storage temperature from+2 to +8 °C
  • Polymerization temperature of pure cyanoacrylates (80-90°C), addition of MS reduces polymerization temperature to 45°C
  • No tissue necrosis
  • Greater film elasticity at the end of polymerization
  • Biocompatibility
Indications for use
  • Neurosurgery
  • Vascular surgery
  • Cardiac surgery
  • General surgery
  • Thoracic surgery
  • Operative gynecology
  • Operative otolaryngology
  • Endoscopy of the digestive tract
  • Neuroradiology, interventional radiology and cardiology
Application technique

The glue begins to harden after 1-2 seconds. The polymerization reaction is complete in 60-90 seconds. Polymerization time depends on the fabric type, the presenting liquids and the amount of the product applied. During polymerization, the glue forms an effective antiseptic barrier that prevents infectious agents’ and pathogens’ penetration found in the surgical environments.

Upon contact with living tissue in a humid environment, the glue quickly polymerizes, forming a thin elastic waterproof film of high tensile strength, that guarantees a strong adhesion to tissues. The film follows the fabric surface relief where it has been applied.

At the end of polymerization, the glue reaches its maximum mechanical strength, no longer obtaining adhesive properties, therefore napkins or surgical dressings can be applied over the wound without the unwanted adhesion risk. The polymerization reaction is accompanied by a temperature increase up to about 45 °C at the application site.

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